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      • Unit 731 - Guide >
        • Background of Biochemical Warfare Development
        • Imperial Japan's Chemical Warfare Development Program
        • Map of Unit 731
        • Personnel of Unit 731
        • Duties of Unit 731
        • Human Experimentation
        • [GRAPHIC] Germ Warfare Attacks
        • Cover Ups After the War
        • [OLD] Cover Ups After the War
      • Philippines' Resistance - Guide >
        • Philippines World War II Timeline
        • The Japanese Invasion & Conquest of the Philippines
        • Bataan Death March
        • Formation of Underground Philippines Resistance
        • Supplies of the Guerrilla Fighters
        • The Hukbalahap
        • Hunter's ROTC
        • Marking's Guerrillas
        • United States Army Forces in the Philippines of Northern Luzon (USAFIP-NL)
        • The Aetas
        • Chinese and Filipino-Chinese Nationalist Guerrilla Units
        • The Female Faces of the Philippine Guerrillas
      • Rising Sun Flag - Guide >
        • History of the Rising Sun Flag
        • Atrocities Committed Under the Flag
        • Rising Sun Flag in Pop Culture
      • Pinay Guerrilleras - Guide >
        • Japanese Occupation of the Philippine Islands: Pinays Answering the Call to Arms
        • The Fierce Heneralas and Kumanders of the Hukbalahap Guerrillas
        • Amazons of the Pacific Theater
        • Filipina American Veterans: Recovering the Extraordinary Feats of the Ordinary Pinays
        • The Legacy of the Asian Women Soldier
      • Fall of Singapore - Guide >
        • Singapore World War II Timeline
        • History of World War II in the Pacific
        • History of Singapore
        • Japan's Conquest in Asia
        • Japan's Invasion of the Malay Peninsula
        • Sook Ching Massacre
        • Double Tenth Incident
        • Social Changes and Challenges in Singapore
        • Voices from Syonan
        • Return to British Rule
      • Three Years and Eight Months - Guide >
        • Hong Kong before WW2
        • Buildup to World War 2
        • The Battle of Hong Kong
        • Life during 3 Years and 8 Months
        • East River Column Guerrilla Fighters
        • Prisoners of War Camps
        • End of Japanese Occupation
        • War Crimes Trials
      • Siamese Sovereignty - Guide >
        • The Land of Smiles
        • The Thai-Japanese Relationship
        • Phibun’s Domestic and International Policies
        • The Free Thai Resistance Movement
        • Post WW2 Aftermath of Thailand
      • The Khabarovsk War Crimes Trial - Guide >
        • Defendants of Khabarovsk War Crime
        • The Japanese Empire and USSR in WW2
        • The Employment of the Bacteriological Weapon in the War
        • Planning of Japan invasion to USSR
      • Unit 731 Cover-up : The Operation Paperclip of the East - Guide >
        • Establishing Manchukuo
        • The Development of Unit 731
        • Plan Kantokuen and Bacteriological Warfare
        • The Downfall of the Japanese WW2 Era
        • Three Stages of Interrogations
        • Lasting Impacts
      • Marutas of Unit 731 - Guide >
        • How did Ishii Shiro start unit 731?
        • A Beta Testing Site
        • Establishing Pingfan
        • Experiences at the Human Experimentation Complex
        • Vivisection at the Unit 731
        • Anta Testing Grounds
        • Overall Advance from the Laboratory Creations
        • The End of the War
      • Prince Konoe Memoir - Guide >
        • Who is Prince Konoe?
        • Preparation to Tripartite Pact
        • Emperor Hirohito and Prince Konoe
        • The End of Prince Konoe
      • Competing Empires in Burma - Guide >
        • What was the China-Burma-India Theater?
        • When did the China-Burma-India Theater Happen?
        • Who Fought in the China-Burma-India Theater?
        • The Second Sino Japanese War
        • Japan in the South
        • Operation U-Go
      • Battle of Shanghai - Guide >
        • The Battle of Shanghai. Background
        • Shanghai Before War
        • The First Battle of Shanghai 1932
        • Battle of Shanghai 1937
        • Aftermath of Battle for Shanghai
      • Ishi Shiro - Guide >
        • History of Biological Weapons and The Young Ishii Shiro
        • Establishment in Manchuria
        • Pingfang District - Harbin
        • Failures and Corruption
        • Post War
      • Taiwan The Israel of the East - Guide >
        • Background of Formosa
        • Industrialization of Japan
        • China During WWII
        • Taiwan under Kuomintang
        • New Taiwanese National Identity
      • Seeking Justice for Biological Warfare Victims of Unit 731 - Guide >
        • Introduction of Wang Xuan
        • Colonel Memorandum
        • The Beginning of Biological Warfare
        • The Bacteriological Warfare on China
        • Victims in Zhejiang’s Testimonies
        • After the War
      • Rice and Revolution - Guide >
        • The French Colonial Period
        • Anti-Colonial Resistance
        • The Rise of the Communist Movement
        • Imperial Japan’s Entry into Indochina
        • The Portents of Famine
        • The Famine (1944-45)
        • Legacy of the 1944-45 Vietnam Famine
      • Clash of Empires - Guide >
        • Japan’s Imperialist Origins
        • Japan’s Competition against the West: Nanshin-ron and Hokushin-ron
        • Japanese Imperialism Through the Lens of French Indochina
        • The U.S.-Japan Relations and the Pearl Harbor Attack
      • Hunger for Power and Self-SufficiencyI - Guide >
        • The Influence of War Rations on Post-War Culinary Transformations
        • How World War II Complicated Food Scarcity and Invention
        • American Military Innovations
        • Government-Sponsored Food Inventions in Europe during World War II
        • Feeding the Army: The Adaptation of Japanese Military Cuisine and Its Impact on the Philippines
        • Mixed Dishes: Culinary Innovations Driven by Necessity and Food Scarcity
      • Denial A Quick Look of History of Comfort Women and Present Days’ Complication - Guide >
        • The Comfort Women System and the Fight for Recognition
        • The Role of Activism and International Pressure
        • The Controversy over Japanese History Textbooks
        • The Sonyŏsang Statue and the Symbolism of Public Memorials
        • Activism and Support from Japanese Citizens
        • The Future of Comfort Women Memorials and Education
      • Echoes of Empire: The Power of Japanese Propaganda - Guide >
        • Brief Overview of Imperial Japan
        • Defining Propaganda
        • Propaganda Encouraging Action​
        • The Rise of Nationalism
        • The Formation of Japanese State Propaganda
        • Youth and Education
      • Shadows of the Rising Sun: The Black Dragon Society and the Dawn of Pan-Asianism - Guide >
        • Origins of the Black Dragon Society
        • The Influence of Pan-Asianism
        • Relationship with Sun Yat-sen
        • The Role in Southeast Asia
        • The Spread of Ideology and Espionage
        • Disbandment and Legacy
      • Chongqing Bombing: The Forgotten Blitz of Asia and Its Lasting Impact - Guide >
        • Introduction and Historical Background
        • The Class Divide During the Bombings
        • Resilience and Unity of Chongqing
        • Key Incidents - Great Tunnel Massacre
        • The Aftermath of the Bombings
        • Legacy and Commemoration
      • Shanghai's International Zone: A Nexus of War, Intelligence, and Survival - Guide >
        • Historical Background
        • The International Zone
        • Battles in Shanghai
        • Civilian Intelligence Efforts
        • Wartime Brutality
        • Aftermath & Legacy
    • Lesson Plans >
      • Reparations
      • Ethics in Science
      • Writing the Narrative of a Pinay Fighter
      • Privilege Journal
      • Environmental Injustices
      • Female Guerrillas
      • Hunter's ROTC
      • Scientific Advancements
      • Seeking Justice: A Humanities Lesson Plan
      • The Hukbalahap
      • Trading Immunity
      • Bataan Death March
      • Biochemical Warfare Development
  • History Remembered
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The Beginning of Biological Warfare

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Ishii Shiro


After the Germans’ use of chemical weapons during the first World War (WWI), on June 17, 1925, during the Geneva Conference, 44 countries passed and signed the Protocol for the Prohibition of the Use in War of Asphyxiating, Poisonous or other Gases, and of Bacteriological Methods of Warfare, also known as the Geneva Protocol. Although Japanese representatives were involved in drafting and signing the Geneva Protocol, it was not ratified in Japan at the time.

Ishii Shiro, who was then a student of bacteriological, serological, and pathological studies at the Graduate School of Kyoto University, was interested in the Geneva Protocol as a curious scientist. He studied the conference reports with Harada Toyoji and other military doctors who attended the conference and noticed that the Geneva Protocol was only for the use of chemical and biological weapons and did not limit any development, manufacture, preservation, and movement of chemical and biological weapons. Upon graduation in April 1928, in a span of two years, Ishii Shiro traveled to 25 European and American countries and observed that research on biological warfare had not advanced in Japan. Four months after his return, he became an instructor at the Imperial Japanese Army Medical School.

Due to Japan’s lack of natural and mineral resources, biological weapons were inexpensive due to their low production costs, automatic transmission, and high potential for lethality. Using those reasons, Ishii convinced the Minister of War to provide funding to establish his network of biological weapons research. Ishii Shiro then became the Minister of Epidemic Prevention of the Kwantung Army.

By August 1932, an epidemic prevention laboratory headed by Ishii Shiro was established with the support of Chikahiko Koizumi (Surgeon General of the Imperial Japanese Army). At the time, the Imperial Japanese Army already had a department for epidemic prevention, meaning that Ishii’s work might be quite different than just epidemic prevention.

The
Togo Unit

Imperial Japan’s successful invasion and occupation of Manchuria presented opportunities for ambitious scientists. Ishii Shiro was so proud of Japan’s accomplishment and he was able to establish a biological research facility named “Togo Unit” after his idolized national hero, General Togo Heihachiro who defeated Russia in the Russo-Japanese War. The “Togo Unit '' operated in Beiyinhe, a village about 70 km southeast of Harbin, conducting human experimentation as early as 1932 in facilities formerly used as a soy sauce factory with high packed earth walls. In order to keep the facilities a highly confidential matter, the Togo Unit staff members were not allowed to communicate with outsiders. This location was exposed during the Mid-Autumn Festival in 1934 when the escape of 16 Chinese prisoners revealed the Unit’s secrets.
​
The Unit was then forced to temporarily relocate to the Army Military Medical School in Tokyo and later to Nangang, Harbin. As a result of the prisoners’ escape in 1934, a more secretive and contained facility was established, later known as Unit 731. On July 29th, 1936, the Togo Unit was issued a notice as a part of the Kwantung Army. Different branches known as “Ishii’s Network” were established to conduct research on different types of biological weapons. In a book written by Tsuneishi Keiichi, Unit 731- The Truth about Biological Weapons and Crimes, he stated that the Ishii Network had a staff exceeding 10,000 people and that Unit 100 in Changchun, Unit 1644 in Nanjing, and Unit 731 in Harbin conducted human experiments on a daily basis.


Related Book

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Get It Now!

Seeking Justice for Biological Warfare Victims of Unit 731: Evidence Collected by Wang Xuan

Unit 731 was established during the Sino-Japanese War in Harbin as a covert biological warfare research and development section of the Imperial Japanese Army. Besides human experimentation, they developed lethal biological weapons as an efficient way to win the war against the world.

In about a decade of existence, they produced a massive amount of germs enough to kill the world three times. Biological weapons such as anthrax, glanders, and bubonic plague were deployed in China during the war. In the Chongshan Village of Yiwu, Zhejiang Province, an epidemic was caused by biological weapons. After the attack, many died from the diseases developed by the biological weapons. Survivors of the incidence end up with rotten legs and cannot live normal lives after the attack.

Wang Xuan had been discovering the truth and fighting for justice for these victims of biological weapons during WW2. This book will provide original documents from the Rockefeller Institute, CIA, and other officials from the United States government from the National Archive and Records Administration.

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Colonel Memorandum

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The Bacteriological Warfare on China

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  • Home
    • About >
      • FAQ's - Frequently Asked Questions
    • Support Us >
      • Projects you can support! >
        • Distributing Books
        • Presenting at 112th Annual Meeting of Pacific Coast Branch
        • Summer Research Relocation Fund
    • Contact
  • Stories
    • Videos >
      • Black Hearts (2021)
    • Blog
    • Podcast: Forgotten History
  • Internship
    • Summer 2025 Internship
    • Spring 2025 Internship
    • Summer 2024 Internship
    • Summer 2023 Internship
    • Fall 2022 Internship
    • Summer 2022 Internship
    • Summer 2021 Internship
    • Fall 2020- Spring 2021 Internship
    • Summer 2020 Internship
    • Fall 2019 Internship
    • Summer 2019 Internship >
      • Public History Night
    • School Year 2018-2019 Internship
    • Summer 2018 Internship >
      • 2018 Summer Showcase + Fundraiser
    • Fall 2017 Internship
    • Summer 2017 Internship >
      • 2017 Summer Showcase & Fundraiser
  • Books
  • Archives
  • Resource Page
    • Supplementary Research Guides >
      • Unit 731 - Guide >
        • Background of Biochemical Warfare Development
        • Imperial Japan's Chemical Warfare Development Program
        • Map of Unit 731
        • Personnel of Unit 731
        • Duties of Unit 731
        • Human Experimentation
        • [GRAPHIC] Germ Warfare Attacks
        • Cover Ups After the War
        • [OLD] Cover Ups After the War
      • Philippines' Resistance - Guide >
        • Philippines World War II Timeline
        • The Japanese Invasion & Conquest of the Philippines
        • Bataan Death March
        • Formation of Underground Philippines Resistance
        • Supplies of the Guerrilla Fighters
        • The Hukbalahap
        • Hunter's ROTC
        • Marking's Guerrillas
        • United States Army Forces in the Philippines of Northern Luzon (USAFIP-NL)
        • The Aetas
        • Chinese and Filipino-Chinese Nationalist Guerrilla Units
        • The Female Faces of the Philippine Guerrillas
      • Rising Sun Flag - Guide >
        • History of the Rising Sun Flag
        • Atrocities Committed Under the Flag
        • Rising Sun Flag in Pop Culture
      • Pinay Guerrilleras - Guide >
        • Japanese Occupation of the Philippine Islands: Pinays Answering the Call to Arms
        • The Fierce Heneralas and Kumanders of the Hukbalahap Guerrillas
        • Amazons of the Pacific Theater
        • Filipina American Veterans: Recovering the Extraordinary Feats of the Ordinary Pinays
        • The Legacy of the Asian Women Soldier
      • Fall of Singapore - Guide >
        • Singapore World War II Timeline
        • History of World War II in the Pacific
        • History of Singapore
        • Japan's Conquest in Asia
        • Japan's Invasion of the Malay Peninsula
        • Sook Ching Massacre
        • Double Tenth Incident
        • Social Changes and Challenges in Singapore
        • Voices from Syonan
        • Return to British Rule
      • Three Years and Eight Months - Guide >
        • Hong Kong before WW2
        • Buildup to World War 2
        • The Battle of Hong Kong
        • Life during 3 Years and 8 Months
        • East River Column Guerrilla Fighters
        • Prisoners of War Camps
        • End of Japanese Occupation
        • War Crimes Trials
      • Siamese Sovereignty - Guide >
        • The Land of Smiles
        • The Thai-Japanese Relationship
        • Phibun’s Domestic and International Policies
        • The Free Thai Resistance Movement
        • Post WW2 Aftermath of Thailand
      • The Khabarovsk War Crimes Trial - Guide >
        • Defendants of Khabarovsk War Crime
        • The Japanese Empire and USSR in WW2
        • The Employment of the Bacteriological Weapon in the War
        • Planning of Japan invasion to USSR
      • Unit 731 Cover-up : The Operation Paperclip of the East - Guide >
        • Establishing Manchukuo
        • The Development of Unit 731
        • Plan Kantokuen and Bacteriological Warfare
        • The Downfall of the Japanese WW2 Era
        • Three Stages of Interrogations
        • Lasting Impacts
      • Marutas of Unit 731 - Guide >
        • How did Ishii Shiro start unit 731?
        • A Beta Testing Site
        • Establishing Pingfan
        • Experiences at the Human Experimentation Complex
        • Vivisection at the Unit 731
        • Anta Testing Grounds
        • Overall Advance from the Laboratory Creations
        • The End of the War
      • Prince Konoe Memoir - Guide >
        • Who is Prince Konoe?
        • Preparation to Tripartite Pact
        • Emperor Hirohito and Prince Konoe
        • The End of Prince Konoe
      • Competing Empires in Burma - Guide >
        • What was the China-Burma-India Theater?
        • When did the China-Burma-India Theater Happen?
        • Who Fought in the China-Burma-India Theater?
        • The Second Sino Japanese War
        • Japan in the South
        • Operation U-Go
      • Battle of Shanghai - Guide >
        • The Battle of Shanghai. Background
        • Shanghai Before War
        • The First Battle of Shanghai 1932
        • Battle of Shanghai 1937
        • Aftermath of Battle for Shanghai
      • Ishi Shiro - Guide >
        • History of Biological Weapons and The Young Ishii Shiro
        • Establishment in Manchuria
        • Pingfang District - Harbin
        • Failures and Corruption
        • Post War
      • Taiwan The Israel of the East - Guide >
        • Background of Formosa
        • Industrialization of Japan
        • China During WWII
        • Taiwan under Kuomintang
        • New Taiwanese National Identity
      • Seeking Justice for Biological Warfare Victims of Unit 731 - Guide >
        • Introduction of Wang Xuan
        • Colonel Memorandum
        • The Beginning of Biological Warfare
        • The Bacteriological Warfare on China
        • Victims in Zhejiang’s Testimonies
        • After the War
      • Rice and Revolution - Guide >
        • The French Colonial Period
        • Anti-Colonial Resistance
        • The Rise of the Communist Movement
        • Imperial Japan’s Entry into Indochina
        • The Portents of Famine
        • The Famine (1944-45)
        • Legacy of the 1944-45 Vietnam Famine
      • Clash of Empires - Guide >
        • Japan’s Imperialist Origins
        • Japan’s Competition against the West: Nanshin-ron and Hokushin-ron
        • Japanese Imperialism Through the Lens of French Indochina
        • The U.S.-Japan Relations and the Pearl Harbor Attack
      • Hunger for Power and Self-SufficiencyI - Guide >
        • The Influence of War Rations on Post-War Culinary Transformations
        • How World War II Complicated Food Scarcity and Invention
        • American Military Innovations
        • Government-Sponsored Food Inventions in Europe during World War II
        • Feeding the Army: The Adaptation of Japanese Military Cuisine and Its Impact on the Philippines
        • Mixed Dishes: Culinary Innovations Driven by Necessity and Food Scarcity
      • Denial A Quick Look of History of Comfort Women and Present Days’ Complication - Guide >
        • The Comfort Women System and the Fight for Recognition
        • The Role of Activism and International Pressure
        • The Controversy over Japanese History Textbooks
        • The Sonyŏsang Statue and the Symbolism of Public Memorials
        • Activism and Support from Japanese Citizens
        • The Future of Comfort Women Memorials and Education
      • Echoes of Empire: The Power of Japanese Propaganda - Guide >
        • Brief Overview of Imperial Japan
        • Defining Propaganda
        • Propaganda Encouraging Action​
        • The Rise of Nationalism
        • The Formation of Japanese State Propaganda
        • Youth and Education
      • Shadows of the Rising Sun: The Black Dragon Society and the Dawn of Pan-Asianism - Guide >
        • Origins of the Black Dragon Society
        • The Influence of Pan-Asianism
        • Relationship with Sun Yat-sen
        • The Role in Southeast Asia
        • The Spread of Ideology and Espionage
        • Disbandment and Legacy
      • Chongqing Bombing: The Forgotten Blitz of Asia and Its Lasting Impact - Guide >
        • Introduction and Historical Background
        • The Class Divide During the Bombings
        • Resilience and Unity of Chongqing
        • Key Incidents - Great Tunnel Massacre
        • The Aftermath of the Bombings
        • Legacy and Commemoration
      • Shanghai's International Zone: A Nexus of War, Intelligence, and Survival - Guide >
        • Historical Background
        • The International Zone
        • Battles in Shanghai
        • Civilian Intelligence Efforts
        • Wartime Brutality
        • Aftermath & Legacy
    • Lesson Plans >
      • Reparations
      • Ethics in Science
      • Writing the Narrative of a Pinay Fighter
      • Privilege Journal
      • Environmental Injustices
      • Female Guerrillas
      • Hunter's ROTC
      • Scientific Advancements
      • Seeking Justice: A Humanities Lesson Plan
      • The Hukbalahap
      • Trading Immunity
      • Bataan Death March
      • Biochemical Warfare Development
  • History Remembered
Contribute